Technology advancement have made our life much easier. we can predict disease, identify genes and discover cells with amazing properties and also visualize them.
Predict cancer in me!
Scientist have developed a new technology that detects distinct genetic changes differentiating cancer patients from healthy individuals and could serve as a future cancer predisposition test. the research team, has created a design for a new DNA Microarray that allows them to measure the 2 million microsatellites (sort, repetative DNA sequences) found within the human genome using 3,00,000 probes.
Found it!( new marker for biliary atresia identified).
Biliary atresia is congenital disease, leading to blockage in tubes carrying bile fluid from liver to gall bladder. Researchers have identified RRAS gene and its related MAPK pathway that play a vital role in the pathogenesis and serves a a noble prognostic marker for biliary atresia. Microarray technology has been used to study the mechanism and allows the simultaneous analysis of thousands of transcripts within a single experiment. Some studies have been performed to investigate the gene expression profiling of livers from BA patients. How ever none of them was designed to identify genes that play a key role in the pathogenesis an prognosis of BA.
Gene behind rare skin cancer that heals itself discovered.
Scientists from the institute of medical biology(IMB) have identified the gene behind a rare skin cancer, which grows rapidly for a few weeks before healing spontaneously. The peculiar behaviour of this rare self-healing cancer, called multiple self-healing squamous epithelioma(MSSE), was discovered to be caused by a failture in the gene called TGFBR-1, which is a key component of a signalling pathway that can also be impaired in other cancers. MSSE patients with faulty TGFBR-1 develops lots of small tumors- but at some point there is a switch in the behaviour and the tumors lacking TGFBR-1 start to shrink and heal by themselves. The research was published in Nature Genetics Today.(ANI).
Scientists develop 3D imaging of individual living cells
A team of scientists at the Arizona State university is working to build a next-generation, 3-dimensional imaging microscope, called a " Cell-CT" scanner, that will perform functional computed tomography (CT) imaging of individual living cells to provide a transformative view of biological structural an functional interrelationships at the single cell level. The Cell-CT scanner may enable, for the first time, rapid 3D spatial localization of protiens, and assessment of their concentration in subcellular compartments and Microdomains, providing powerful insights concerning relationships between cell structure and function in disease. Thus enables scientists to gain new insights into the metabolic pathways of disease, such as cancer.
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